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Yet recent studies have shown no significant difference between oral methylprednisolone (a steroid) and intravenous methylprednisolone in terms of efficacy and safety.17 The most common side effects of these drugs, however, are mild to moderate in severity. Some research has indicated that oral methylprednisolone may cause increased breast fat and development of breast cancer.18 The use of oral methylprednisolone is not recommended, and oral prednisolone therapy should not be considered for the prevention of breast cancer. Oral prednisolone is a potent steroid which increases the production of hormones, especially estrogen and progesterone, by the adrenal gland. Oral methylprednisolone is an effective, though not always safe, treatment for acne, methylprednisolone thuốc.17 Oral prednisolone is not recommended for the management of any skin conditions on the face or on the trunk of the penis, methylprednisolone thuốc.19,20
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